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. 2020 Jan 2;10(1):73. doi: 10.3390/biom10010073

Table 3.

Factors and responses of CG-PEG-CSO-SPIONs in the BBD.

Factor Level
Low (−) Medium (0) High (+)
X1 = CTAB concentration (mg/mL) 2.5 5.0 7.5
X2 = CSO concentration (mg/mL) 0.1 0.2 0.3
X3 = PEG concentration (mg/mL) 0.1 0.2 0.3
Response Constraint
Y1 = Particle size (nm) Minimize
Y2 = Zeta potential (mV) ≥ ±20 mV
Y3 = LE (%) Maximize
Y4 = LC (%) Maximize