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Compound 6 prevented glutamate-induced HT22 cell death. (A) Microscopic images were obtained after exposure of HT22 cells to glutamate for 24 h (scale bar, 50 μm). (B) Cell viability was measured using a CyTox assay kit 24 h after the treatment with 5 mM glutamate with or without tetrahydrocannabinol (THC). Bars denote the percentage of cell viability (mean ± S.E.M). (C) DPPH scavenging activity was determined based on the elimination of DPPH radicals.
