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. 2020 Jan 12;9(1):69. doi: 10.3390/antiox9010069

Table 5.

Interactions between the representatives of the dominant polyphenols of C. bullatus and C. zabelii leaves.

Phenolic Mixture Concentration Ratio (µg/mL) Theoretical Effective Concentration (µg/mL) Experimental Effective Concentration (µg/mL) IF ± 95% Conf. Effect
ECA:QPH 1:4 2.09 1.81 ± 0.01 0.93 ± 0.01 synergy
1:2 1.80 1.81 ± 0.07 1.04 ± 0.04 additivity
1:1 1.74 1.52 ± 0.01 0.98 ± 0.01 additivity
2:1 1.48 1.38 ± 0.01 0.99 ± 0.01 additivity
4:1 1.39 1.17 ± 0.01 0.91 ± 0.01 synergy
ECA:CHA 1:4 1.56 1.36 ± 0.03 0.89 ± 0.02 synergy
1:2 1.39 1.23 ± 0.01 0.85 ± 0.01 synergy
1:1 1.41 1.24 ± 0.01 0.91 ± 0.01 synergy
2:1 1.25 1.15 ± 0.08 0.89 ± 0.06 synergy
4:1 1.26 1.04 ± 0.13 0.84 ± 0.10 synergy
CHA:QPH 1:4 2.19 2.00 ± 0.02 0.93 ± 0.01 synergy
1:2 1.97 1.89 ± 0.02 0.92 ± 0.01 synergy
1:1 1.99 1.99 ± 0.09 1.03 ± 0.05 additivity
2:1 1.78 1.87 ± 0.09 1.02 ± 0.05 additivity
4:1 1.79 1.81 ± 0.19 1.03 ± 0.11 additivity

Results are mean values ± SD (n = 3). IF, interaction factor, calculated according to Equation (2). Codification of the phenolic compounds is given in Figure 1.