Figure 2.
Pretreatment with CC or FCC relieved depression-like behavior and weakened oxidative stress in stress-induced rats. (a) Experimental design of rat immobilization stress. The (b) immobility time and (c) climbing time was measured in the forced swim test (FST). The oxidative stress markers (d,f) malondialdehyde (MDA) and (e,g) nitric oxide (NO) were estimated in rat hippocampus and serum by Thiobarbituric acid reactive substances (TBARS) and Griess reagent kits. “+, -”: Rats were treated with or without CC extract, FCC extract or stress. The data are expressed as mean ± SD, n = 8. # p < 0.05, ## p < 0.01, ### p < 0.001 compared to the control group, * p < 0.05, ** p < 0.01, *** p < 0.001 compared to stress group, and $ p < 0.05, $$ p < 0.01 compared to CC 100 group.