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Biotransformation of silymarin components (10 mg/L) by human fecal microbiota from four healthy donors without pre-incubation under simulated gastric and subsequently small-intestinal conditions. The results are shown as the area under the curve (AUC) of the respective peak in LC/MS chromatograms (logarithmic scale) as a function of time of incubation (mean ± SEM, n = 4); minor metabolites with AUC < 1% were excluded for better clarity.
