Table 1.
The concentration (µM) of the parent flavonolignans during the fecal biotransformation.
| Compound | 0 | 6 | 12 | 24 | 48 h |
|---|---|---|---|---|---|
| Silybin A | 7.0 ± 1.2 | 7.6 ± 0.8 | 7.8 ± 1.2 | 10.4 ± 0.5 | 8.5 ± 1.8 |
| Silybin B | 5.8 ± 1.1 | 6.7 ± 0.7 | 6.5 ± 1.1 | 9.5 ± 0.8 | 6.7 ± 2.0 |
| Silychristin A | 29.0 ± 0.5 | 29.6 ± 0.4 | 33.5 ± 1.3 | 5.1 ± 1.2 | 3.5 ± 0.2 |
| Silychristin B | 4.8 ± 0.1 | 3.8 ± 0.1 | 1.2 ± 0.1 | 0.4 ± 0.0 | 0.5 ± 0.1 |
| Silydianin | 69.9 ± 0.9 | 70.1 ± 8.0 | 55.8 ± 5.4 | 19.7 ± 3.6 | 13.1 ± 1.0 |
| 2,3-Dehydrosilybin (A + B) | 57.4 ± 3.8 | 47.8 ± 2.3 | 54.2 ± 1.0 | 60.6 ± 5.4 | 57.5 ± 1.1 |
Data are presented as mean ± standard error, n = 3.