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. 2020 Jan 13;10(1):143. doi: 10.3390/nano10010143

Table 1.

Pharmacokinetic Parameters for C60-[64Cu]Cu(NOTA) and [64Cu]Cu(NOTA) 1..

Material Distribution Half-Life [min] Distribution Rate Constant (α) [min−1] Elimination Half-Life [min] Elimination Rate Constant (β) [min−1] Clearance (CL) [cc/min] Area under Curve (AUC) [%ID·min/cc]
C60-[64Cu]Cu(NOTA) 0.6436 1.077 7.078 9.793 × 10−2 3.161 × 10−5 3.164 × 102
[64Cu]Cu(NOTA) 0.4975 1.393 8.153 8.501 × 10−2 3.152 × 10−5 3.173 × 102

1 Two-phase decay model: R2 = 0.966 for C60-[64Cu]Cu(NOTA) and for [64Cu]Cu(NOTA).