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. 2020 Jan 3;10(1):78. doi: 10.3390/biom10010078

Figure 2.

Figure 2

Voltage sensitivity is not conferred to the translocon by the signal peptide. (A–C) Closings of SecY(S329C)EG crosslinked to the signal peptide of OmpA (21C) at φ = −140 mV. The voltage protocol is shown in red above. (D) SecYEG in complex with empty ribosome also closes in response to voltage. Note the shorter time scale here as compared to (A,C). The small schemes obey the color code from Figure 1: with the signal peptide in light blue, nascent chain in blue and the cross-link depicted as X.