Table 2.

Central-composite design matrix defining conditions for the production of CCP, together with the experimental values of the respective responses.

Run	Variables in Uncoded Unit		d (nm)	ζ (mV)	PDI	GAE (μg/mg)
	EEP (%)	Chitosan (%)
1	1	0	760	−26.8	0.35	2.57
2	2.5	0.5	1080	61.1	0.29	3.82
3	0.4	0.5	1140	59.8	0.41	0.23
4	4.5	0.5	720	60	0.42	5.07
5	2.5	0.5	780	59.5	0.42	5.00
6	4	1	1080	55.4	0.26	2.67
7	2.5	0	1130	44.1	0.62	4.41
8	4	0	510	32.7	0.44	7.77
9	2.5	0.5	850	55.6	0.37	3.35
10	1	1	1250	54.6	0.38	0.52
11	2.5	1	1360	55.2	0.41	1.51
12	2.5	0.5	650	59.6	0.25	5.09
13	2.5	0.5	750	61.2	0.31	8.8
14	1	0	760	−26.8	0.35	2.57