Figure 5.

ZIKV infection in a DENV-naïve mother is reported. Diagnosis was performed using molecular, serological, and immunological assays, and transmission to the fetus was reported. cMRI/cUS: cerebral magnetic resonance imaging/cerebral ultrasonography; PRNT: plaque reduction neutralization test; WOP: week of pregnancy; EIA: enzyme immunoassay; IFA: immunofluorescence assay; Nt-Ab; neutralizing antibodies. In the box of molecular diagnosis, black numbers specify the week of pregnancy, while red numbers in brackets indicate the exact day of gestation. BOB assay result is expressed as the ratio of inhibition, while ELISpot assay is measured as net spots/million PBMC.