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. 2019 Dec 29;9(1):31. doi: 10.3390/antiox9010031

Figure 7.

Figure 7

A-ITC and P-ITC treatments inhibit the overexpression of CD11b/c and NOS2 in the hippocampus of mice with osteoarthritis pain. The relative protein levels of (A) CD11b/c, (B) GFAP, and (C) NOS2 in the hippocampus of MIA-injected mice treated with A-ITC, P-ITC, or vehicle are presented. The SS-injected mice treated with vehicle were used as controls. (D) Representative blots for CD11b/c (160 kDa), GFAP (50 kDa), NOS2 (110 kDa), and GAPDH (37 kDa). All proteins are expressed relative to GAPDH levels. In all panels, * denotes significant differences vs. SS-injected mice treated with vehicle, # vs. MIA-injected mice treated with A-ITC and $ vs. MIA-injected mice treated with P-ITC (p < 0.05; one-way ANOVA followed by the Student–Newman–Keuls test). The results are presented as the mean ± SEM; n = 4 samples per experimental group.