Figure 1.

Preparation of Dendropanax morbifera water extract (DP) and experimental design for streptozotocin (STZ)-induced nephrotoxicity in rats. (A) High-performance liquid chromatography (HPLC)-UV chromatogram for DP extract. Major components in DP extract were identified and quantified by using HPLC analysis. HPLC analysis was carried out via gradient elution on a Phenomenex Kinetex C18 column (150 × 4.6 mm, 5 µm). The flow rate, column oven temperature, and UV wavelength for detection were set at 1 mL/min, 30 °C, and 254 nm, respectively. (B) Representative chromatogram on standard compounds (neochlorogenic acid, syringin, chlorogenic acid, and rutin). (C) The chemical structures of major compounds in DP extract and the regression equations and correlation coefficients for the four standard compounds. (D) The regression equation and correlation coefficient (R²) for three standards.