Table 3.
Group | Week 0 | Week 1 | Week 2 | Week 3 | Week 4 | Change (%) |
---|---|---|---|---|---|---|
NC | 131 ± 8.01 | 132.33 ± 1.52 | 129.33 ± 1.15 | 130.33 ± 1.527 | 131.66 ± 2.08 | 0.50 (i/c) |
STZ | 423.33 ± 40.05 a | 515 ± 61.55 a | 563.33 ± 32.15 a | 593 ± 11.27 a | 599.33 ± 0.58 a | 41.57 (i/c) |
DP | 134 ± 4.36 a | 127.66 ± 3.21 a,b | 128.66 ± 1.15 b | 129.66 ± 0.57 b | 129 ± 4.58 b | −3.73(d/c) |
STZ + DP | 432 ± 44.50 b | 318.33 ± 96.02 a,b | 233.66 ± 104.04 b | 150 ± 26.46 b | 131.67 ± 9.07 b | −69.52 (d/c) |
STZ + Mef | 422 ± 32.36 a | 347.33 ± 40.77 a,b | 258.67 ± 4.51 a,b | 171.67 ± 6.03 a,b | 139 ± 7.21 b | −67.06 (d/c) |
Values are presented as means ± SD. n = 5; one way analysis of variance (ANOVA) was used for the comparison of means. Differences between means were significant at p < 0.05 using the Bonferroni’s multiple comparison test. a p < 0.05 in comparison with the normal control group; b p < 0.05 in comparison with STZ (diabetic control) group. i/c, Increase; d/c, Decrease.