Table 3.

InVivo_GISPlus individual and average parameter values. Median values and the fitted values for the average subjects are also shown for comparison. SD: standard deviation; CV: coefficient of variation. K_empt is the gastric emptying rate constant; K_TD and K_TJ represent the transit rate constants in the duodenal and jejunal compartment, respectively; K_Diss represent the intestinal dissolution rate constant; V1 and V2 represent the duodenal and jejunal residual volumes, respectively.

Parameter	KEMPT (1/h)	K_TD (1/h)	K_TJ (1/h)	K_Diss mL/(ug*h)	V1 (mL)—Duodenal	V2 (mL)—Jejunal
Average	0.84	1.99	0.13	0.10	155.11	70.64
SD	1.27	3.01	0.25	0.36	128.44	80.48
CV%	151.84	150.83	196.68	361.28	82.81	113.93
B003V1	0.39	0.20	0.130	0.101	80.4	20.0
B004V1	0.08	0.59	0.059	1.48 × 10−3	73.9	18.5
B004V2	0.02	1.86	0.209	5.05 × 10−3	195.4	209.2
B005V1	0.51	0.22	0.010	1.61 × 10−4	15.3	2.5
B005V2	0.18	0.45	0.224	3.62 × 10−4	350.5	84.5
B006V1	0.95	1.84	0.042	3.51 × 10−4	123.2	64.6
B017V1	0.16	0.41	0.081	5.75 × 10−3	62.8	10.2
B017V2	0.07	0.08	0.036	1.11 × 10−3	77.6	19.5
B042V1	0.13	10.26	0.000	7.31 × 10−2	29.0	5.2
B042V2	0.05	0.19	0.086	1.52 × 10−3	150.0	80.6
B049V1	0.05	0.19	0.086	1.52 × 10−3	262.3	10.6
B049V2	0.05	0.19	0.086	1.52 × 10−3	150.0	80.6
B052V1	2.79	2.99	0.019	6.96 × 10−4	19.0	27.6
B053V1	1.24	1.79	0.039	3.48 × 10−4	137.8	215.8
B055V1	4.05	0.47	0.100	9.00 × 10−5	126.6	50.0
B055V2	3.65	0.07	0.001	4.33 × 10−4	119.6	93.4
B063V1	1.00 × 10−3	4.12	1.140	1.96 × 10−3	115.9	56.3
B065V1	0.20	2.51	0.092	0.121	500.0	283.1
B065V2	1.28	9.48	0.002	1.59	357.7	10.1
Median	0.18	0.47	8.1 × 10−2	1.52 × 10−3	123.24	49.99
Average Subject	0.45	0.47	7.9 × 10−2	9.34 × 10−4	136.53	56.89