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Pharmacokinetic disposition parameters between observed and simulated data applying the default settings.
| Pharmacokinetic (PK) Parameters | Observed Pharmacokinetic Data | Simulated Pharmacokinetic Data |
|---|---|---|
| Plasma Cmax (µg/mL) | 41.7 | 32.5 |
| Plasma Tmax (h) | 3.0 | 3.0 |
| Plasma AUC0-∞ (µg·h/mL) | 259 | 189 |
| Plasma AUC0-28h (µg·h/mL) | 255 | 189 |
