Table 2.

Multivariate Cox regression for 28-day mortality (propensity-matched population: n = 186)

	HR	95% CI	p
Net fluid balance	1.00	1.00–1.00	< 0.001
Steroids use*	4.66	1.94–11.18	0.001
Hyperlactatemia**	3.61	1.41–9.22	0.007
VE-VPs	0.31	0.17–0.57	< 0.001

SOFA Sequential Organ Failure Assessment, VE-VPs very early start of vasopressor support

*Low-dose steroids (200–300 mg/day) used in the context of shock

**Lactate levels > 2.0 mmol/L (Third International Consensus Definitions for Sepsis and Septic Shock—Sepsis 3.0—considers the presence of suspected infection accompanying life-threatening organ dysfunction, use of vasopressors, MAP < 65 mmHg, and lactate levels > 2 mmol/L as septic shock)