Table 1.
The clinical characteristics of patients on peritoneal dialysis grouped by albumin-globulin ratio
| Variable | Total | Lower AGR | Higher AGR | p |
|---|---|---|---|---|
| Demographics | ||||
| Gender (male, n, %) | 356 (59.1%) | 171 (54.8%) | 185 (63.8%) | 0.025 |
| Age (y) | 50.33 ± 14.63 | 53.88 ± 13.14 | 46.52 ± 15.20 | < 0.001 |
| Body mass index (kg/m2) | 22.97 ± 3.32 | 22.99 ± 3.28 | 22.96 ± 3.38 | 0.915 |
| Primary disease | ||||
| primary glomerular diseases(N,%) | 349 (58.0%) | 168 (53.8%) | 181 (62.4%) | |
| Diabetic nephropathy(N,%) | 91 (15.1%) | 64 (20.5) | 27 (9.3%) | |
| hypertensive nephropathy(N,%) | 57 (9.5%) | 28 (9.0%) | 29 (10.0%) | |
| Obstructive nephropathy(N,%) | 70 (11.6%) | 37 (11.9%) | 33 (11.4%) | |
| Other(N,%) | 35 (5.8%) | 15 (4.8%) | 20 (5.9%) | |
| Comorbidities | ||||
| CVD (N,%) | 153 (25.4%) | 85 (27.2%) | 68 (23.4%) | 0.285 |
| Diabetes (n,%) | 141 (23.4%) | 91 (29.2%) | 50 (17.2%) | 0.001 |
| CCI Score | 3.00 (3.00) | 4.00 (2.00) | 3.00 (2.00) | < 0.001 |
| Hypertension(N,%) | 556 (92.4%) | 289 (92.6%) | 267 (92.1%) | 0.796 |
| Laboratory variables | ||||
| Leukocytes(109/L) | 6.85 (2.34) | 7.07 (2.71) | 6.72 (2.21) | 0.009 |
| Hemoglobin (g/L) | 97.13 ± 13.71 | 96.82 ± 13.52 | 97.47 ± 13.93 | 0.559 |
| Platelet(109/L) | 236.20 ± 77.69 | 250.40 ± 82.03 | 220.87 ± 69.65 | < 0.001 |
| RDW(%) | 14.95 (2.21) | 15.25 (2.39) | 14.73 (2.15) | < 0.001 |
| Blood glucose (mmol/L) | 4.50 (1.03) | 4.52 (1.24) | 4.49 (0.89) | 0.154 |
| Albumin-corrected calcium (mmol/L) | 2.24 (0.21) | 2.26 (0.20) | 2.23 (0.20) | 0.036 |
| Phosphorus (mmol/L) | 1.66 (0.62) | 1.62 (0.53) | 1.72 (0.67) | 0.018 |
| Serum Globulin (g/L) | 26.47 ± 4.67 | 29.30 ± 4.07 | 23.42 ± 3.08 | NA |
| Serm Albumin (g/L) | 32.58 ± 4.22 | 30.89 ± 3.91 | 34.41 ± 3.77 | NA |
| Cholesterol (mmol/L) | 4.37 (1.01) | 4.37 (1.14) | 4.35 (0.92) | 0.515 |
| Triglycerides (mmol/L) | 1.43 (0.96) | 1.43 (0.97) | 1.43 (0.91) | 0.470 |
| Serum uric acid (μmol/L) | 432.12 ± 89.07 | 430.00 ± 88.57 | 434.41 ± 89.70 | 0.544 |
| Serum creatinine (μmol/L) | 792.84 (332.21) | 758.25 (307.50) | 832.77 (351.44) | < 0.001 |
| Urea nitrogen (mmol/L) | 19.50 (7.36) | 18.91 (6.90) | 20.14 (7.85) | 0.002 |
| 24 h urine (ml) | 846.31 (600.00) | 846.31 (642.50) | 846.31 (562.50) | 0.562 |
| Peritoneal dialysate volume(L/day) | 7.97 ± 0.83 | 7.99 ± 0.87 | 7.95 ± 0.78 | 0.484 |
| Total KT/V | 2.15 (0.85) | 2.20 (0.73) | 2.06 (0.89) | 0.058 |
| PDGC(%) | 1.50 (0.25) | 1.50 (0.25) | 1.50 (0.00) | 0.002 |
Abbreviations: AGR Albumin-globulin ratio, CVD Cardiovascular disease, CCI Charlson comorbidity index, RDW Red cell distribution width, PDGC Peritoneal dialysate glucose concentration, NA Not applicable