Table 2.

A list of circRNAs encoded in human cancers

Gene names	Cancer type	Encoded protein name	Cancer phenotype	Refs
circSHPRH	Glioma	SHPRH-146aa	The overexpression of SHPRH-146aa glioblastoma cells reduces their malignant behavior and tumorigenicity in vitro and in vivo	[96]
circLINC-PINT	Gliobalstoma	PINT87aa	It can suppress glioblastoma cell proliferation in vitro and in vivo	[98]
circβ-catenin	hepatocellular carcinoma	β-catenin-370aa	Silencing of circβ-catenin significantly suppresses malignant phenotypes in vitro and in vivo	[102]
circFBXW7	Glioma Breast cancer	FBXW7-185aa	Knockdown of FBXW7-185aa promoted malignant phenotypes in vitro and in vivo	[97] [103]
circAKT3	Glioblastoma	AKT3-174aa	Knockdown of circ-AKT3 enhanced the malignant phenotypes of astrocytoma cells	[101]
circPPP1R12A	Colon cancer	circPPP1R12A-73aa	circPPP1R12A played a critical role in proliferation, migration and invasion of colon cancer cells	[100]