Table 2.

Assessment on the methodological strategies of the included studies

Trial ID	Random sequence generation	Allocation concealment	Blinding	Incomplete outcome data	Selective outcome reporting	Other sources of bias
Uwe Reuter 2018	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
David W Dodick 2017	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Peter J. Goadsby 2017	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Hong Sun 2016	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
David W Dodick 2014	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
David W. Dodick 2018	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Marcelo E Bigal 2015	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Vladimir Skljarevski 2018	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Vladimir Skljarevski 2017	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
Virginia L. Stauffer 2018	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk
David W Dodick 2014	Low risk	Low risk	Low risk	Low risk	Low risk	Unclear risk