Table 3.
Oxidative stress markers among the studied groups.
| Groups | Malonaldehyde (mmol/g tissue) | Nitric oxide (μmol/g tissue) | Glutathione reduced (μmol/g protein) | Super oxide dismutase (U/mg protein) | Nitric oxide synthase (pmol/min/mg protein) | Catalase (mol/min/gm) |
|---|---|---|---|---|---|---|
| Control | 77.93 ± 5.88 | 150.84 ± 19.25 | 23.47 ± 3.56 | 21.09 ± 2.86 | 18.03 ± 2.61 | 1.05 ± 0.11 |
| CCl4 | 111.17 ± 18.21 | 205.51 ± 25.30 | 14.78 ± 3.02 | 14.11 ± 3.96 | 28.36 ± 5.01 | 0.66 ± 0.24 |
| Free media | 110.71 ± 16.80 | 205.76 ± 26.19 | 14.51 ± 3.45 | 14.37 ± 3.82 | 29.27 ± 3.26 | 0.64 ± 0.22 |
| CCl4+Nilotinib | 83.97 ± 14.78 | 176.39 ± 22.37 | 23.85 ± 5.08 | 19.70 ± 4.42 | 20.14 ± 5.66 | 0.99 ± 0.21 |
| CCl4+stem cell exosomes | 96.480 ± 28.41 | 173.25 ± 26.41 | 21.32 ± 3.37 | 18.33 ± 3.25 | 20.04 ± 2.85 | 0.80 ± 0.26 |
| CCl4+stem cell exosomes+Nilotinib | 80.10 ± 17.83 | 148.02 ± 14.02 | 23.28 ± 5.24 | 22.80 ± 3.82 | 18.98 ± 3.27 | 1.02 ± 0.21 |
| P value | <0.001∗ | <0.001∗ | <0.001∗ | <0.001∗ | <0.001∗ | <0.001∗ |