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. 2020 Feb 12;8:e8548. doi: 10.7717/peerj.8548

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©2020 Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) The protein–protein interaction network of overlapping upregulated DEGs at 3 and 4 weeks. The red represents significantly upregulated mRNAs in GK rats at the age of 3 and 4 weeks. (B) The protein–protein interaction network of overlapping downregulated DEGs at 3 and 4 weeks. The blue represents significantly downregulated mRNAs in GK rats at the age of 3 and 4 weeks. (C) The top 10 upregulated mRNAs ranked by node degree. The darker of the color indicates the higher of connectivity degree. (D) The top 10 downregulated mRNAs ranked by node degree. The darker of the color indicates the higher of connectivity degree.