Table 3.
Results of Cox Multivariate Analysis
| Endpoint | Parameter | Chi-square | p-value | Hazard Ratio (HR) | 95% HR Lower | 95% HR Upper |
|---|---|---|---|---|---|---|
| OS | WHO | 19.540 | <0.001 | 2.331 | 1.601 | 3.393 |
| Radicality | 14.177 | <0.001 | 2.020 | 1.401 | 2.914 | |
| Squamous | 7.258 | 0.007 | 2.240 | 1.245 | 4.029 | |
| T | 6.639 | 0.010 | 1.513 | 1.104 | 2.073 | |
| N | 7.097 | 0.007 | 2.131 | 1.221 | 3.719 | |
| RT technique | 5.823 | 0.016 | 0.659 | 0.469 | 0.924 | |
| Tumor vol. | 9.571 | 0.002 | 1.745 | 1.226 | 2.482 | |
| CSS | WHO | 14.616 | <0.001 | 2.341 | 1.514 | 3.620 |
| T | 8.42013 | 0.004 | 1.779 | 1.206 | 2.626 | |
| N | 4.709 | 0.030 | 2.173 | 1.078 | 4.383 | |
| Elective vol. | 7.721 | 0.005 | 0.137 | 0.792 | 1.591 | |
| RFS | T | 17.396 | <0.001 | 2.052 | 1.464 | 2.877 |
| Dose | 9.881 | 0.002 | 0.353 | 0.185 | 0.676 | |
| Tumor vol. | 10.326 | 0.001 | 1.978 | 1.305 | 2.999 | |
| LRFS | T | 9.565 | 0.002 | 1.898 | 1.264 | 2.850 |
| Dose | 5.436 | 0.019 | 0.391 | 0.177 | 0.861 | |
| Tumor vol. | 4.926 | 0.026 | 1.793 | 1.071 | 3.002 |
Abbreviations: p, significance level; CI, confidence interval; RT, radiotherapy; OS, overall survival; CSS, cancer-specific survival; RFS, relapse-free survival; LRFS, local relapse-free survival; T, tumor; N, nodes; vol, volume.