Table 2.
Univariate Analysis of Risk Factors Associated with Postoperative Complications
| Characteristics | All (n=154) | Postoperative Complications | P-value | |
|---|---|---|---|---|
| Yes (n=80) | No (n=74) | |||
| Age,year | 64.9±11.4 | 64.4±12.2 | 65.4±10.6 | 0.607 |
| Sex,n(%) | 0.004 | |||
| Male | 95(61.7) | 58(72.5) | 37(50) | |
| Female | 59(38.3) | 22(27.5) | 37(50) | |
| Body mass index, kg/m2 | 23.7±3.5 | 23.4±3.6 | 23.9±3.5 | 0.382 |
| Chronic disease,n(%) | 0.907 | |||
| Hypertension | 59(38.3) | 28(35.0) | 31(41.9) | |
| Diabetes mellitus | 25(16.2) | 15(18.8) | 10(13.5) | |
| Dyslipidemia | 10(6.5) | 5(6.3) | 5(6.8) | |
| Hepatocirrhosis | 1(0.6) | 1(1.3) | 0(0.0) | |
| Preoperative CRP,mg/L | 6.9±10.5 | 8.7±13.4 | 4.9±5.2 | 0.018 |
| Preoperative albumin, g/L | 37.1±3.7 | 36.5±4.2 | 37.8±3.1 | 0.032 |
| Preoperative CAR | 0.2±0.4 | 0.3±0.5 | 0.1±0.1 | 0.019 |
| Preoperative mGPS≥1,n(%) | 26(16.9) | 21(26.3) | 5(6.8) | 0.002 |
| Surgical approach, n(%) | 0.782 | |||
| Laparoscopy | 132(85.7) | 70(87.5) | 62(83.8) | |
| Converted laparoscopy | 8(5.2) | 4(5.0) | 4(5.4) | |
| Laparotomy | 14(9.1) | 6(7.5) | 8(10.8) | |
| Operative time, minutes | 216.2±94.2 | 235.1±99.5 | 195.7±84.0 | 0.009 |
| Estimated blood loss, mL | 164.4±647.7 | 239.4±891.5 | 83.3±79.0 | 0.123 |
| Location of the tumor,n(%) | 0.152 | |||
| Colon | 74(48.1) | 34(42.5) | 40(54.1) | |
| Rectum | 80(51.9) | 46(57.5) | 34(45.9) | |
| Neoadjuvant treatment,n(%) | 9(5.8) | 9(11.3) | 0(0.0) | 0.003 |
| Pathological stage, n(%) | 0.534 | |||
| pCR | 2(1.3) | 1(1.3) | 1(1.4) | |
| 0 | 1(0.6) | 0(0.0) | 1(1.4) | |
| I | 42(27.3) | 20(25.0) | 22(29.7) | |
| II | 49(31.8) | 27(33.7) | 22(29.7) | |
| III | 46(29.9) | 22(27.5) | 24(32.4) | |
| IV | 14(9.1) | 10(12.5) | 4(5.4) | |
| CRP on POD3, mg/L | 57.1±49.8 | 73.9±54.0 | 38.9±4.4 | <0.001 |
| Albumin on POD3, g/L | 33.2±3.7 | 32.4±3.8 | 34.0±3.6 | 0.009 |
| CAR on POD3 | 1.8±1.7 | 2.4±1.8 | 1.2±1.1 | <0.001 |
| poGPS≥1 on POD3,n(%) | 20(13.0) | 18(22.5) | 2(2.7) | <0.001 |
Notes: Data represent mean ± standard deviation or frequency, as appropriate.
Abbreviations: CRP, C-reactive protein; CAR, C-reactive protein/albumin ratio; mGPS, modified Glasgow Prognostic Score; pCR, pathologic complete response; POD, postoperative day; poGPS, postoperative Glasgow Prognostic Score.