Figure 8.
Mechanism of nanofiber composite membrane that promotes endogenous healing of tendon and prevents exogenous adhesion. The inner layer of freeze-dried amnion contains several active factors, such as TGF-β1, bFGF, VEGF, and PDGF. These factors are slowly released to the tendon repair area through the porous network structure of PCL nanofibers, which promotes the proliferation of tenocytes and the synthesis of collagen. The outer layer of PCL nanofibers functions as a barrier to fibroblasts and other exogenous tissue invasion.