A STMs showing the effect of the Orai channel inhibitor GSK 7975A (1 & 10 μM), on ICC-SS Ca2+ transients. B Summary data showing the effect of GSK 7975A, on ICC-SS Ca2+ transient frequency, amplitude, duration and spatial spread, c=17, n=5. C STMs showing that the stimulatory effect of 2-APB (10 μM) on ICC-SS Ca2+ transients was reversed by GSK 7975A (1 μM). D Summary data showing the effect of GSK 7975A on ICC-SS Ca2+ transient frequency, amplitude, duration and spatial spread in the presence of 2-APB (10 μM), c=10, n=3.