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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Physiol. 2020 Jan 30;598(4):651–681. doi: 10.1113/JP279102

Fig. 16: Inhibitory neural effects on ICC-SS Ca2+ transients are due to sGC.

Fig. 16:

A STMs showing the effect of the sGC activator Bay 58–2667 (1 μM) on ICC-SS Ca2+ transients. B Summary effect of Bay 58–2667 on ICC-SS Ca2+ transient frequency, c=11, n=4. C STMs of the effect of EFS (10 Hz, 10 sec) on ICC-SS Ca2+ transients in the presence of atropine (1 μM) before and after addition of the sGC inhibitor ODQ (10 μM). D Summary effects of EFS in the presence of atropine on the frequency, amplitude, duration and spatial spread of Ca2+ transients, comparing activity before and during EFS and comparing the effects of EFS and the effects of EFS + ODQ, c=15, n=7.