A STMs showing the effect of the cholinergic agonist, carbachol (CCh, 1 μM), on ICC-SS Ca2+ transients, in the presence of 1 μM TTX. B Summary data showing the effect of CCh on ICC Ca2+ transient frequency, amplitude, duration and spatial spread, c=12, n=4. C STMs of the effect of EFS (10 Hz, 10 sec) on ICC-SS Ca2+ transients in the presence of L-NNA (100 μM) and MRS 2500 (1 μM). D Summary effects of EFS in the presence of L-NNA + MRS 2500 on the frequency, amplitude, duration and spatial spread of ICC-SS Ca2+ transients, c=13, n=5.