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. 2019 Dec 17;91(3):314–320. doi: 10.1136/jnnp-2019-321794

Table 4.

Sample size estimates for distinguishing posited reductions in dystonia spread cumulative probability over 2 years by onset site

Power Cervical Blepharospasm Hand Laryngeal
50% reduction
 80 498 (996) 59 (118) 293 (586) 227 (454)
 90 666 (1332) 79 (158) 393 (786) 303 (606)
30% reduction
 80 1639 (3278) 178 (356) 959 (1918) 737 (1474)
 90 2194 (4388) 238 (476) 1283 (2566) 986 (1972)

Values are shown as size of treated/untreated groups and total sample size in parentheses under assumption of equal allocation across groups.