Table 2.

Table comparing the series of model variants constructed to dissect the most important contributors to the positive regulation by P

Name	Base model	Properdin included?	Parametric change
MM	MM	No	–
MM	MM	No	$k_6=k_{22}=0.023$ min${}^{-1}$
+ long lived C3bBb
Properdin binds C3b	PM	Yes	$k_{17}=k_{23}=k_{24}=0$
Properdin binds C3bB	PM	Yes	$k_{13}=k_{17}=0$
Properdin binds C3bBb	PM	Yes	$k_{13}=k_{23}=k_{24}=0$
Properdin model	PM	Yes	–

MM and PM refer to minimal model and properdin model, respectively. Parametric change refers to the change in the model variant with respect to the base model