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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Virology. 2019 Dec 30;541:160–173. doi: 10.1016/j.virol.2019.12.011

Figure 9. vIRFs are not needed for efficient suppression of type I IFN production during primary lytic infection of HDLMECs.

Figure 9.

(A) Schematic of the experiment. Primary HDLMECs were infected by WT or ΔvIRF KSHV for 48 hours followed by SeV infection for 6 hours. (B) IFNβ gene expression in the absence of SeV infection was analyzed by RT-qPCR at 54 hpi. (C) IFNβ in the supernatant was measured by bead-based immunoassay. (D) IFNβ gene expression in the presence of SeV infection was measured by RT-qPCR at 54 hpi. Dashed line indicates the limit of assay detection. Error bars represent standard deviation (n=3). ns: non-significant.