2,4-dianilinopyrimidine |
AP26113 |
9.6 |
13.6 |
2 |
20 |
60 |
16 |
2,4-dianilinopyrimidine |
ALK-IN-1 |
10.6 |
14.9 |
3 |
34 |
62 |
28 |
2,4-dianilinopyrimidine |
TAE684 |
9.5 |
13.3 |
42 |
87 |
97 |
|
2,4-dianilinopyrimidine |
TAE226 |
6.6 |
10.5 |
90 |
97 |
104 |
|
2,4-dianilinopyrimidine |
CZC 25146 |
4 |
9.1 |
93 |
101 |
96 |
|
2-aminopyrimidine |
CHIR99021 |
0.2 |
1 |
96 |
101 |
98 |
|
2-anilino-4-alkyl-aminopyrimidine |
PF03814735 |
7 |
11 |
20 |
70 |
92 |
227 |
2-anilino-4-alkyl-aminopyrimidine- |
BX912 |
1.7 |
7.6 |
26 |
90 |
100 |
|
2-anilino-4-alkyl aminopyrimidine |
BX795 |
2 |
9.1 |
33 |
80 |
97 |
|
2-anilino-4-alkyl-aminopyrimidine |
MRT67307 |
2.3 |
9.6 |
35 |
86 |
92 |
|
2-anilino-4-aryl-pyrimidine |
AZD 3463 |
12.2 |
12.7 |
26 |
74 |
103 |
185 |
2-anilino-4-aryl-pyrimidine |
Pacritinib |
7.4 |
10.1 |
31 |
78 |
96 |
|
4,6-disubstituted-pyrimidine |
BGJ 398 |
0.2 |
0 |
96 |
99 |
100 |
|
Amide hinge binder |
Gilteritinib |
10 |
11.7 |
18 |
74 |
84 |
204 |
Aminobenzothiazole (Type II) |
TAK632 |
5.9 |
2.3 |
82 |
87 |
92 |
|
Aminopyrazole |
XL228 |
8.6 |
9.9 |
26 |
65 |
94 |
|
Aminopyrazole |
PF3758309 |
6.2 |
9.6 |
71 |
78 |
95 |
|
Aminotriazole |
CDK 1/2 Inhibitor III |
9.2 |
13.3 |
3 |
17 |
69 |
19 |
Azaindole |
GSK650394 |
15.8 |
20.7 |
3 |
4 |
14 |
3 |
Benzimidazole |
CP 673451 |
12.6 |
16.8 |
17 |
46 |
88 |
73 |
Benzimidazole |
Crenolanib |
13.9 |
17.6 |
47 |
92 |
118 |
|
Benzimidazole |
GSK461364 |
0 |
1.6 |
92 |
96 |
95 |
|
Flavone |
Alvocidib |
7 |
5.9 |
29 |
62 |
102 |
|
Fused pyrimidine |
BI2536 |
8.9 |
9.9 |
54 |
70 |
101 |
96 |
Fused pyrimidine |
BI6727 |
7.7 |
7.9 |
75 |
94 |
104 |
|
Fused pyrimidine |
Milciclib |
7 |
9.5 |
76 |
105 |
107 |
|
Fused pyrimidine |
MLN 0905 |
1.2 |
0.3 |
86 |
95 |
99 |
|
Fused pyrimidine |
MK1775 |
4.2 |
5.3 |
99 |
99 |
101 |
|
Imidazopyridazine (Type II) |
Ponatinib |
9.4 |
10.9 |
53 |
92 |
99 |
|
Indazole |
KW2449 |
5.3 |
6.4 |
42 |
84 |
96 |
|
Miscellaneous |
STO 609 |
7.6 |
11.3 |
21 |
56 |
63 |
58 |
Oxindole |
JAK3 Inhibitor VI |
7.8 |
12.4 |
21 |
81 |
87 |
26 |
Oxindole |
PHA665752 |
* |
* |
67 |
93 |
109 |
|
Oxindole |
SU6656 |
* |
* |
71 |
86 |
95 |
|
Oxindole |
Hesperadin |
8.6 |
11.5 |
84 |
95 |
99 |
|
Oxindole |
BIO |
13.4 #
|
7.2 #
|
89 |
100 |
102 |
|
Purine |
Aminopurvalanol |
6.9 |
8.3 |
22 |
80 |
100 |
|
Pyrazolo-pyrimidine |
LDN 193189 |
4.8 |
9.1 |
50 |
62 |
68 |
146 |
Pyrazolo-pyrimidine |
Dorsomorphin |
7.4 |
8.9 |
58 |
96 |
100 |
|
Pyridine (Type II) |
Rebasitinib |
6.4 |
8.7 |
81 |
93 |
95 |
|
Pyrrolotriazine |
Brivanib |
0.7 |
0 |
100 |
100 |
101 |
|
Quinoline |
OTSSP167 |
16.6 |
16.7 |
0 |
49 |
84 |
86 |
Quinoline |
Pelitinib |
5.8 |
8.1 |
60 |
84 |
100 |
|
Quinolines |
GSK1059615 |
2 |
6.7 |
34 |
81 |
92 |
|
Quinolines |
Ro 3306 |
0 |
5.8 |
88 |
94 |
94 |
|
Staurosporine Analogue |
Lestaurtinib |
18.4 |
16.3 |
3 |
33 |
64 |
25 |
Staurosporine Analogue |
K252a |
16.7 |
15.3 |
31 |
4 |
99 |
|
Staurosporine Analogue |
Midostaurin |
15.2 |
12.8 |
38 |
82 |
97 |
|
Staurosporine Analogue |
SB 218078 |
22.3 |
9.8 |
64 |
86 |
98 |
|
Staurosporine Analogue |
Go6976 |
9.6 |
9 |
80 |
92 |
97 |
|
Staurosporine Analogue |
Ro 31-8220 |
1.9 |
5.7 |
85 |
100 |
100 |
|
Triazolopyridine |
Filgotinib |
0 |
0.5 |
72 |
86 |
96 |
|