Table 6.
Compound | IC50 (µM) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
A375 | H1299 | HepG2 | HT29 | HCC1937 | ||||||
24 h | 72 h | 24 h | 72 h | 24 h | 72 h | 24 h | 72 h | 24 h | 72 h | |
1 | 5.22 | 0.69 | 8.63 | 1.32 | 4.22 | 0.89 | 4.69 | 0.85 | 9.68 | 2.62 |
2 | 7.18 | 0.95 | 10.3 | 2.62 | 5.67 | 1.35 | 6.12 | 1.12 | 11.6 | 3.11 |
3 | 40.3 | 11.3 | >50 | 26.3 | 11.3 | 5.03 | 13.0 | 4.33 | >50 | 12.6 |
4 | 6.04 | 0.78 | 10.1 | 2.15 | 5.16 | 1.11 | 5.37 | 1.02 | 10.3 | 2.89 |
cis-platinum | 23.1 | 9.32 | 21.2 | 7.3 | >50 | 18.9 | >50 | >50 | >50 | >50 |