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. 2020 Jan 16;18(1):58. doi: 10.3390/md18010058

Table 6.

Inhibitory concentration (IC50, µM) of compounds 14 against various tumor cell lines (cis-platinum as positive control).

Compound IC50 (µM)
A375 H1299 HepG2 HT29 HCC1937
24 h 72 h 24 h 72 h 24 h 72 h 24 h 72 h 24 h 72 h
1 5.22 0.69 8.63 1.32 4.22 0.89 4.69 0.85 9.68 2.62
2 7.18 0.95 10.3 2.62 5.67 1.35 6.12 1.12 11.6 3.11
3 40.3 11.3 >50 26.3 11.3 5.03 13.0 4.33 >50 12.6
4 6.04 0.78 10.1 2.15 5.16 1.11 5.37 1.02 10.3 2.89
cis-platinum 23.1 9.32 21.2 7.3 >50 18.9 >50 >50 >50 >50