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Downregulation of PD-L1 protein via inhibition of Akt and p65 phosphorylation in MDA-MB231 cells treated with hesperidin: (A) Phosphorylation of Akt, (B) phosphorylation of p65, and (C,D) PD-L1 protein in the absence or presence of inhibitor (PI3K/Akt LY294002 inhibitor and NF-κB inhibitor BAY) Statistical significance * p < 0.05 and ** p < 0.01.
