Table 2.
Effects of G15 on the fibrinolytic system in rats.
| Index | Injection | a Concentration (mg/kg) | |||
|---|---|---|---|---|---|
| 0 | 1 | 6 | 12 | ||
| t-PA (ng/mL) | HP | 23.86 ± 3.80 | 46.97 ± 5.07 | 65.24 ± 10.75 | 65.72 ± 4.23 |
| G15 | 23.86 ± 3.80 | 35.64 ± 4.66 | 41.22 ± 8.16 | 62.73 ± 2.66 | |
| u-PA (ng/mL) | HP | 1.12 ± 0.06 | 1.01 ± 0.07 | 1.23 ± 0.09 | 1.41 ± 0.14 |
| G15 | 1.12 ± 0.64 | 1.22 ± 0.11 | 1.39 ± 0.24 | 1.58 ± 0.17 | |
| PAI-1 (ng/mL) | HP | 12.80 ± 1.57 | 37.50 ± 17.56 | 33.21 ± 11.95 | 24.05 ± 5.93 |
| G15 | 12.80 ± 1.57 | 25.63 ± 6.46 | 9.46 ± 0.52 | 6.03 ± 1.74 | |
| t-PA/PAI-1 | HP | 1.86 ± 0.07 | 1.25 ± 0.68 | 1.96 ± 0.39 | 2.73 ± 0.31 |
| G15 | 1.86 ± 0.07 | 1.39 ± 0.44 | 4.35 ± 0.62 | 10.40 ± 1.26 | |
a Different concentrations of G15 were formulated in normal saline.