Table 2.
Summary of investigations related to the cardiovascular effects of BGP-15.
Main Effect | Dose |
---|---|
Reconstruction of diastolic dysfunction [17] | 10 mg/kg BGP-15, per os |
100 mg/kg metformin, per os | |
Amelioration of cardiac function and reduction of arrhythmic episodes [18] | 15 mg/kg BGP-15 |
50 µM BGP-15 on the cells | |
Endogenous HSP overexpression and protection against tachycardia remodeling [57] | 1 mM BGP-15 |
Reduction of ROS levels and cell injury during ischemia–reperfusion [11] | The medium contained 40 mg/L of BFP-15 |