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. 2020 Jan 20;25(2):429. doi: 10.3390/molecules25020429

Table 2.

Summary of investigations related to the cardiovascular effects of BGP-15.

Main Effect Dose
Reconstruction of diastolic dysfunction [17] 10 mg/kg BGP-15, per os
100 mg/kg metformin, per os
Amelioration of cardiac function and reduction of arrhythmic episodes [18] 15 mg/kg BGP-15
50 µM BGP-15 on the cells
Endogenous HSP overexpression and protection against tachycardia remodeling [57] 1 mM BGP-15
Reduction of ROS levels and cell injury during ischemia–reperfusion [11] The medium contained 40 mg/L of BFP-15