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. 2020 Jan 20;25(2):429. doi: 10.3390/molecules25020429

Table 4.

Summary of the performed investigations related to the aforementioned effects of BGP-15.

Main Effect Dose
Reduction of the toxic side effects of taxol and cisplatin without compromising their antitumor effect [19] 50, 100, 200 mg/kg of BGP-15, per os, once daily throughout the experiment
1.5 mg/kg cisplatin, intraperitoneally, once daily, for 5 days
5 mg/kg taxol, intraperitoneally, every other day for 10 days
Reversal of oxidative damage in the heart, caused by imatinib [38] 200 µM BGP-15
Prevention of the development of acute renal failure caused by cisplatin treatment [21] 100, 200 mg/kg BGP-15 shortly before cisplatin treatment
Alleviation of oxaliplatin-induced intestinal dysfunction, which eased the gastrointestinal side-effects of chemotherapy [50] 15 mg/kg BGP-15
3 mg/kg oxaliplatin