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Neither paclitaxel nor RgIA4 significantly affected body weight over time. Changes in rat body weight (in g) are indicated following treatment with a total dose of 8 mg/kg paclitaxel, with or without RgIA4 at 80 or 16 μg/kg. Readings were taken from cohorts of n = 8 rats per group, unless otherwise specified. Black circles: vehicle-saline; red squares: PTX-saline; blue triangles: PTX-RgIA4 (16 μg/kg); hollow green triangles: PTX-RgIA4 (80 μg/kg). Mean +/- SEM are indicated.
