Table 3.
IC50 of synthesized thiosemicarbazones 2a–k and 3a–j.
| Comp. No. | IC50 of Synthesized Compounds (μM) | ||||||
|---|---|---|---|---|---|---|---|
| Gram (+) | Gram (−) | Fungus | |||||
| EF | SA | BC | EC | PA | SE | CA | |
| 2a | 24.78 | 4.78 | 4.12 | - | - | - | 6.78 |
| 2b | 10.78 | 8.99 | 12.45 | - | - | - | 3.57 |
| 2c | 5.68 | 9.66 | 8.24 | - | - | - | 3.45 |
| 2d | 4.89 | - | 25.22 | - | 24.67 | - | 5.35 |
| 2e | 25.89 | 6.78 | 6.09 | - | - | - | 5.56 |
| 2f | 12.78 | 7.88 | 7.82 | - | - | - | 6.35 |
| 2g | 6.78 | 7.89 | 6.88 | - | - | - | 3.24 |
| 2h | 11.67 | 6.24 | 7.56 | - | 27.45 | - | 4.57 |
| 2i | 12.78 | 12.56 | 12.11 | - | - | - | 3.57 |
| 2j | 6.88 | 22.67 | 22.12 | - | - | - | 4.34 |
| 2k | 47.89 | 6.45 | 8.49 | - | - | - | 5.68 |
| 3a | 6.34 | 6.99 | 12.33 | - | - | - | 3.67 |
| 3b | 25.89 | 8.99 | 9.91 | - | - | - | 7.89 |
| 3c | 28.99 | 50.22 | 40.45 | - | - | - | 5.67 |
| 3d | 17.89 | 21.45 | 25.89 | - | - | - | 6.78 |
| 3e | 4.67 | 9.23 | 10.11 | - | - | - | 3.22 |
| 3f | 13.57 | 21.44 | 11.88 | - | - | - | 3.67 |
| 3g | 4.78 | 35.67 | 32.11 | - | - | - | 5.34 |
| 3h | 12.56 | 7.88 | 9.85 | - | - | - | 6.79 |
| 3i | 12.57 | 15.67 | 25.62 | - | - | - | 7.89 |
| 3j | 35.46 | 6.46 | 7.49 | - | - | - | 4.67 |
EF: Enterococcus faecalis ATCC13124; SA: Staphylococcus aureus ATCC25923; BC: Bacillus cereus ATCC 13245; EC: Escherichia coli ATCC25922; PA: Pseudomonas aeruginosa ATCC27853; SE: Salmonella enterica ATCC12228; CA: Candida albicans ATCC10231; -: inactive.