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a) Anti-vascular endothelial growth factor receptor (VEGFR) treatment decreased osteopontin (OPN) and osterix (OSX) in peri-implant tissue at two weeks post-implantation. b) The treatment also decreased OPN in tissue on implant surface at four weeks. c) Representative image of tissue on implant surface. Scale bar: 250 μm. DAPI, diamidino-2-phenylindole.
