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. 2020 Jan 18;25(2):407. doi: 10.3390/molecules25020407

Table 1.

Poly (ADP-ribose) polymerase 1 (PARP-1) enzyme inhibitory activity of Talazoparib and compound 3.

Test Compound Inhibition of PARP-1 Enzyme
IC50 (μM)
Talazoparib 0.005
3 1.919