Flow chart depicting LA and coagulation testing in discrepant (A, B) and consistently positive (C) groups. In total, 4328 dRVVT/PNT combination assays were evaluated. The study population included patients ranging in age from 4 months to 93 years with a female:male ratio of 1·7:1. PTT assays were performed in all three groups at a high rate. PT was not as frequently performed, but was prolonged in many of those tested: A, 51·2% (64/125); B, 22·1% (30/136); and C, 29·9% (38/127) (data not shown). PTT testing with the addition of polybrene showed patients with unfractionated heparin anticoagulation: A, 10·1% (10/99); B, 31·9% (36/113); and C, 11·7% (23/196), (data not shown). LA, lupus anticoagulant; dRVVT, dilute Russell Viper Venom Test; PNT, phospholipid-neutralization test; PTT, partial thromboplastin time; PT, prothrombin time.