Deficiency of CAII protein in CAII knockout mice detected by Western blotting. (a) Detection of CAII protein in the liver, kidney, heart, and lung tissue homogenates from wild type (WT, CAII+/+), heterozygous (Het, CAII+/−), or homozygous (Homo, CAII−/−) knockout mice. (b) Detection of CAII protein in aortic tissue homogenates. (c) Detection of CAII protein in red blood cell ghosts