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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Epilepsy Behav. 2020 Jan 10;103(Pt A):106839. doi: 10.1016/j.yebeh.2019.106839

Fig. 1.

Fig. 1.

The Lafora Epilepsy Cure Initiative (LECI) is funded by NIH grant NS097197. The primary investigator’s and projects for the grant are Drs. Gentry — Science #1: Personalized diagnosis — defining how glycogen metabolism and proteostasis impact LD; Minassian — Science #2: Genome editing, mRNA suppression, and glycogen chain termination to inhibit glycogen storage as therapy for LD; Roach — Science #3: Suppressing glycogen storage with small molecule inhibitors as a therapeutic approach to LD; and Guinovart — Science #4: Defining the therapeutic window for the treatment of LD.