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Screening of antiherpetic drugs for topical efficacy. Drugs were prepared at a concentration of 3% in PLO vehicle and applied to the area of skin where virus had been applied. Mice were treated at 4 and 8 h after inoculation on the day of infection (0 dpi) and 3 times daily at 5-h intervals on 2 through 6 dpi. Survival through 14 dpi is shown.
