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. 2020 Feb;70(1):56–66. doi: 10.30802/AALAS-CM-18-000134

Table 1.

Neurologic scores of BV-inoculated treated with topical ganciclovir or cidofovir

Neurologic score
Maximum Survivors at 14 dpi
Topical ganciclovir
 0% (control) 5 (5, 5); n = 23 no survivors
 0.1% 5 (5, 5); n = 28 0 (0, 0); n = 6
 0.3% 5 (5, 5); n = 28 0 (0, 0.5); n = 6
 0.5% 5 (2, 5); n = 28 1.5 (0, 2); n = 11
 1% a3 (1, 5); n = 28 0.5 (0, 2); n = 19
 3% a1.75 (0, 2.9); n = 28 0 (0, 1); n = 28
 5% *0 (0, 1); n = 28 0 (0, 0); n = 28
% cidofovir
 0% (control) 5 (5, 5); n = 15 no survivors
 0.001% 5 (5, 5); n = 20 no survivors
 0.003% 5 (5, 5); n = 20 0 (0, 0); n = 4
 0.005% 5 (5, 5); n = 10 no survivors
 0.01% 0.5 (0, 5); n = 20 0 (0, 0); n = 13
 0.03% a0 (0, 0); n = 20 0 (0, 0); n = 18
 0.05% a0 (0, 0); n = 10 0 (0, 0); n = 10
 0.1% a0 (0, 0.75); n = 20 0 (0, 0); n = 16
 0.3% a0 (0, 0); n = 20 0 (0, 0); n = 20
 1% a0 (0, 0); n = 9 0 (0, 0); n = 9
 3% a0 (0, 0); n = 9 0 (0, 0); n = 9
 5% a0 (0, 0); n = 9 0 (0, 0); n = 9

Data are presented as the median (lower quartile, upper quartile); number of mice in group.

a

Value is significantly (P < 0.05) different from maximal neurologic score of control mice.