Table 2.

Lesions and BV antigen (detected by immunohistochemistry) in the skin and dorsal root ganglia of mice inoculated with BV and treated topically with vehicle (control), 5% ganciclovir, or 0.5% cidofovir

	Skin (at time point [dpi])						Dorsal root ganglion (at time point [dpi])
	Lesion			Immunohistochemistry			Lesion			Immunohistochemistry
	1	2	3	1	2	3	1 dpi	2 dpi	3 dpi	1 dpi	2 dpi	3 dpi
Control	+*	+++	+++	+	+++	+++	—	—	+++	—	—	+++
Ganciclovir	+*	+	+	—	+	+	—	—	—	—	—	—
Cidofovir	+*	—	—	—	—	—	—	—	—	—	—	—

+, mild lesions that are not virus-specific or lesions present in only 1 individual per group; +++, virus-specific lesions with discernible intranuclear inclusion bodies in the majority of animals per group; *, lesions consistent with skin scarification procedure; –, no lesions