Table 3.
Comparison of long-term oncological outcomes between resected patients with transitional HCC-CC, HCC, and MFCCC
| Outcomes | Transitional HCC-CC, mean (95% CI) | HCC, mean (95% CI) | p value* | MFCCC, mean (95% CI) | p value° |
|---|---|---|---|---|---|
| DFS, months | 14.2 (0.3–28.1) | 43.1 (18–68.2) | 0.001 | 17.8 (4.4–31.2) | 0.061 |
| DFS rate, % | |||||
| 1-year | 46.5 (33.1–59.8) | 72.8 (32.4–113.1) | 0.030 | 59.6 (33.4–85.8) | 0.074 |
| 3-year | 24.6 (18.8–30.3) | 47.4 (21.8–72.9) | 0.022 | 34.2 (17.9–50.3) | 0.078 |
| 5-year | 15 (0.9–28.9) | 31.6 (10.5–52.6) | 0.001 | 20.3 (3.7–28.2) | 0.275 |
| OS, months | 37.1 (22.4–51.7) | 66.8 (47.4–86) | 0.016 | 32.2 (19.8–44.4) | 0.375 |
| OS rate, % | |||||
| 1-year | 66.6 (54.7–78.4) | 84.4 (79.4–89.4) | 0.032 | 66.6 (40.5–92.6) | 0.089 |
| 3-year | 41.5 (30.5–52.4) | 65.2 (56.5–73.9) | 0.017 | 37.8 (14.4–61.1) | 0.057 |
| 5-year | 32.7 (20.5–44.8) | 47.5 (37.5–57.4) | 0.024 | 30.3 (17.7–42.7) | 0.065 |
This table details the long-term oncological outcomes of patients who underwent liver resection. Mean DFS and OS are reported and compared between the 3 different types of primary liver malignancy.
p value*: correlation between transitional HCC-CC and HCC; p value°: correlation between transitional HCC-CC and MFCCC. Statistically significant values are expressed in bold.
DFS, disease-free survival; OS, overall survival; HCC-CC, hepatocholangiocarcinoma; HCC, hepatocellular carcinoma; MFCCC, mass-forming cholangiocarcinoma.