Table 3.

Health and economic benefits over a 10-year period (2018–27) for the base-case scenario

	African region	Region of the Americas	Eastern Mediterranean region	European region	South-East Asia region	Western Pacific region	All Gavi countries
Averted rotavirus burden
Cases	64 941 257	2 279 644	14 727 951	3 514 830	66 895 132	6 202 581	158 561 393
Visits	23 883 590	938 830	5 922 875	859 706	15 531 821	1 674 650	48 811 472
Hospitalisations	2 826 609	78 392	392 566	93 906	2 096 962	244 059	5 732 494
Deaths	376 560	3293	57 927	2547	130 824	5417	576 567
DALYs*	9 407 363	89 129	1 488 332	73 308	3 472 376	152 446	14 682 955
Averted health-care costs (US$)
Government perspective*	192 412 959	15 216 757	26 438 853	14 047 862	186 275 477	49 726 662	484 118 569
Societal perspective*	351 173 250	26 076 818	51 733 623	24 427 446	345 072 153	79 549 803	878 033 093
Vaccine programme costs (US$)
With Gavi subsidy* (cost to country only)	1 211 762 128	105 071 230	375 178 351	93 259 104	2 360 479 712	208 622 785	4 354 373 309
Without Gavi subsidy* (cost to country and to Gavi)	2 187 656 303	129 326 733	550 683 257	104 171 153	2 459 017 468	217 671 893	5 648 526 807
Cost per DALY averted (US$)
Government perspective*†	108 (29–568)	1008 (71–3389)	234 (42–463)	1081 (196–5396)	626 (242–4529)	1042 (137–2661)	264 (202–428)
Societal perspective*	195	1158	335	1088	609	906	325
Cost per DALY averted (government perspective) as a proportion of GDP per capita‡	0·09	0·30	0·17	0·50	0·33	0·49	0·16

DALYs=disability-adjusted life-years. GDP=gross domestic product.

^*Discounted values.

^†Figures in parentheses show 95% uncertainty intervals (2·5th and 97·5th percentiles of 1000 simulations).

^‡GDP per capita in current US$ calculated for each region.