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. 2019 Nov 7;7(12):e1655–e1663. doi: 10.1016/S2214-109X(19)30444-9

Table 2.

Data inputs and model assumptions

Point estimate (95% CI) Source
Population characteristics
Annual global BCG eligible birth cohort 129·1 million 9
Annual all-cause childhood deaths in birth cohort in children aged 0–4 years 6·8 million 11
Annual all-cause childhood deaths in birth cohort in children aged 5–9 years 643 000 11
Annual all-cause childhood deaths in birth cohort in children aged 10–14 years 560 000 11
HIV-negative paediatric male tuberculosis deaths in 2016 110 000 (75 000–151 000) 13
HIV-negative paediatric female tuberculosis deaths in 2016 91 000 (60 000–129 000) 13
Tuberculosis deaths in children younger than 5 years who had received tuberculosis treatment in 2015 (HIV negative) 2690 (1850–4180) 14
Tuberculosis deaths in children younger than 5 years who had not received tuberculosis treatment in 2015 (HIV negative) 161 000 (108 000–223 000) 14
Tuberculosis deaths in children aged 5–15 years who had received tuberculosis treatment in 2015 (HIV negative) 2050 (1510–3100) 14
Tuberculosis deaths in children aged 5–15 years who had not received tuberculosis treatment in 2015 (HIV negative) 31 500 (18 600–51 400) 14
Vaccine characteristics
Vaccine efficacy against tuberculosis death, % 66% (8–88) 3
Vaccine efficacy by age at administration Constant regardless of age of administration Assumption
Duration of protection 15 years 21
Waning of protection None Assumption