Table 3.
Odds ratio of abnormal QTc based on comorbidity.
| Initial analysis | Odds ratio | 95% CI | p value |
| Moderate vs. normal-mild OSA | 0.78 | 0.36-1.67 | 0.19 |
| Severe vs. normal-mild OSA | 1.44 | 0.72-2.92 | 0.1 |
| BMI (kg/m2) | 0.99 | 0.95-1.02 | 0.4 |
| Age (years) | 0.99 | 0.97-1.02 | 0.6 |
| Hypertension | 1.36 | 0.66-2.88 | 0.41 |
| HF | 4.07 | 2.1-8.06 | <0.0001 |
| Subsequent analysis (dichotomous groups) | Odds ratio | 95% CI | p value |
| Severe vs. nonsevere OSA | 2.68 | 1.34-5.48 | 0.0058 |
| BMI (kg/m2) | 0.96 | 0.92-1 | 0.05 |
| Age (years) | 0.99 | 0.96-1.02 | 0.62 |
| Hypertension | 1.42 | 0.59-3.67 | 0.45 |
| HF | 5.41 | 2.63-11.35 | <0.0001 |
Classification of apnea-hypopnea index (AHI) in trichotomous stratification: normal-mild: <15/hr, moderate: 15-30/hr, and severe: >30/hr. For dichotomous stratification: nonsevere: <30/hr (i.e., normal-mild and moderate), severe: >30/hr. OSA = obstructive sleep apnea; BMI = body mass index; HF = heart failure; CI = confidence interval.